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Pep2-8

CAT: 0804-HY-P2276-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-P2276-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pep2-8 is a PCSK9 inhibitor with a binding KD of 0.7 μM and an IC50 of 1.4 μM[1].
CAS Number
[1541011-97-5]
UNSPSC
12352209
Hazard Statement
H302, H315, H319, H335
Target
PCSK9
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pep2-8.html
Purity
99.74
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N[C@H](C(N)=O)C(C)C)[C@@H](NC([C@H](CC(O)=O)NC([C@H](CC(C)C)NC([C@@H](NC([C@H](CCC(O)=O)NC([C@H](CCC(O)=O)NC([C@@H](NC([C@H](CO)NC([C@@]([C@H](O)C)([H])NC([C@@H](NC([C@H](C(C)C)NC([C@H]([C@H](O)C)NC(C)=O)=O)=O)CC1=CC=CC=C1)=O)=O)=O)CC2=CNC3=CC=CC=C23)=O)=O)=O)CC4=CC=C(O)C=C4)=O)=O)=O)CC5=CNC6=CC=CC=C56
Molecular Formula
C83H110N16O24
Molecular Weight
1715.85
Precautions
H302, H315, H319, H335
References & Citations
[1]Yingnan Zhang, et al. Identification of a small peptide that inhibits PCSK9 protein binding to the low density lipoprotein receptor. J Biol Chem. 2014 Jan 10;289 (2) :942-55.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Scientific Category
Peptides
Clinical Information
No Development Reported

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