RS-18286

CAT: 0804-HY-P2110Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-P2110Size:1 Each
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Description
RS-18286 is a potent luteinizing-hormone (LH) -releasing hormone (LHRH) antagonist. RS-18286 blocks the pituitary LHRH receptor and suppresses pituitary luteinizing-hormone (LH) secretion and reduce serum concentrations of gonadal steroids[1].
CAS Number
[109458-76-6]
UNSPSC
12352209
Target
GnRH Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/rs-18286.html
Smiles
C[C@H](C(O)=O)NC([C@H]1N(C([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@@H](CCCC/N=C(NCC)/NCC)NC([C@H](CC2=CC=C(O)C=C2)NC([C@H](CO)NC([C@@H](CC3=CNC4=C3C=CC=C4)NC([C@@H](CC5=CC=C(Cl)C=C5)NC([C@@H](CC6=CC=C(Cl)C=C6)NC(C)=O)=O)=O)=O)=O)=O)=O)=O)=O)CCC1)=O
Molecular Formula
C74H101Cl2N17O14
Molecular Weight
1523.61
References & Citations
[1]Lincoln GA, et al. Compensatory response of the luteinizing-hormone (LH) -releasing hormone (LHRH) /LH pulse generator after administration of a potent LHRH antagonist in the ram. Endocrinology. 1987 Jun;120 (6) :2245-50.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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