SAMβA

• UNSPSC Description:

  SAMβA is conjugated to the cell permeable peptide TAT47-57. SAMβA, a rationally designed selective antagonist of Mfn1-βIIPKC association. SAMβA is a selective inhibitor of mitofusin 1-βIIPKC association improves heart failure outcome in rats[1].

• Target Antigen:

  PKC

• Type:

  Peptides

• Related Pathways:

  Epigenetics;TGF-beta/Smad

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/samβa.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC([C@H](CC1=CC=CC=C1)NC([C@H](CCCNC(N)=N)NC([C@H](CC(O)=O)NC([C@@H](NC([C@H](CC(N)=O)NC([C@H](CCC(O)=O)NC([C@H](C)NC([C@H](CC(N)=O)NC([C@@H](N)CCCNC(N)=N)=O)=O)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O)=O

• Molecular Weight:

  1168.22

• References & Citations:

  [1]Julio C B Ferreira A selective inhibitor of mitofusin 1-βIIPKC association improves heart failure outcome in rats. Nat Commun. 2019 Jan 18;10(1):329.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2429946-75-6