SAM-315

• Target:

  5-HT Receptor

• Related Pathways:

  Neuroscience|||GPCR/G Protein

• Bioactivity:

  SAM-315 (WAY-255315) is a potent antagonist of 5-Hydroxytryptamine-6 (5-HT6), with Ki and IC50 values of 1.1 nM and 4.6 nM, respectively. SAM-315 notably enhances the release of acetylcholine and glutamate in the hippocampus of the brain.

• Smiles:

  O=S (=O) (C1=NNC=2C=CC (=CC21) N3CCNCC3) C4=CC=CC=5C=CC=CC54

• Molecular Formula:

  C21H20N4O2S

• Molecular Weight:

  392.474

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  744218-85-7