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SAMe-1,4-Butanedisulfonate

CAT: 0804-HY-W105505-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W105505-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SAMe-1,4-Butanedisulfonate, a natural compound, is a methyl donor in the central nervous system. SAMe-1,4-Butanedisulfonate has antidepressant activity. SAMe-1,4-Butanedisulfonate can be used for research of CNS disorders[1][2][3][4].
CAS Number
101020-79-5
UNSPSC
12352200
Hazard Statement
H315, H319, H335
Target
Biochemical Assay Reagents
Type
Biochemical Assay Reagents
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/same-1-4-butanedisulfonate.html
Concentration
10mM
Purity
98.03
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=S(CCCCS(=O)(O)=O)(O)=O.NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](C[S+](CC[C@H](N)C(O)=O)C)O3.O=S(CCCCS(=O)([O-])=O)([O-])=O.[1/2]
Molecular Formula
C15H23N6O5S·C4H10O6S2·1/2C4H8O6S2
Molecular Weight
725.79
Precautions
H315, H319, H335
References & Citations
[1]Delle Chiaie R, et al. Efficacy and tolerability of oral and intramuscular S-adenosyl-L-methionine 1,4-butanedisulfonate (SAMe) in the treatment of major depression: comparison with imipramine in 2 multicenter studies. Am J Clin Nutr. 2002 Nov;76 (5) :1172S-6S. |[2]Barceló HA, et al. Osteoartritis experimental y su evolución bajo tratamiento con S-adenosil-L-metionina (SAMe) [Experimental osteoarthritis and its course when treated with S-adenosyl-L-methionine]. Rev Clin Esp. 1990 Jun;187 (2) :74-8. Spanish. |[3]Stramentinoli G, et al. Protective role of S-adenosyl-L-methionine on liver injury induced by D-galactosamine in rats. Biochem Pharmacol. 1978 May 15;27 (10) :1431-3. |[4]Sales AJ, et al. S-adenosyl-l-methionine antidepressant-like effects involve activation of 5-HT1A receptors. Neurochem Int. 2023 Jan;162:105442.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported

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