PSI (TFA)

• Description :

  PSI (TFA) is a potent proteasome inhibitor. PSI (TFA) inhibits the proliferation of primary effusion lymphoma (PEL) cells. PSI (TFA) can be used for the research of Kaposi’s sarcoma-associated herpesvirus (KSHV) infection and KSHV-associated lymphomas[1].

• Product Name Alternative :

  Proteasome Inhibitor 1 (TFA) ; Z-Ile-Glu (OtBu) -Ala-Leu-CHO (TFA)

• UNSPSC :

  12352209

• Target :

  Proteasome

• Type :

  Peptides

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Cancer; Infection

• Assay Protocol :

  https://www.medchemexpress.com/psi-tfa.html

• Solubility :

  10 mM in DMSO

• Smiles :

  OC(C(F)(F)F)=O.O=C([C@H]([C@@H](C)CC)NC(OCC1=CC=CC=C1)=O)N[C@@H](CCC(OC(C)(C)C)=O)C(N[C@@H](C)C(N[C@H](C=O)CC(C)C)=O)=O

• Molecular Formula :

  C34H51F3N4O10

• Molecular Weight :

  732.78

• References & Citations :

  [1] Saji C, et al. Proteasome inhibitors induce apoptosis and reduce viral replication in primary effusion lymphoma cells. Biochem Biophys Res Commun. 2011; 415 (4) :573-8.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported