PSI (TFA)

CAT: 0804-HY-P1258ASize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-P1258ASize:1 Each
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Description
PSI (TFA) is a potent proteasome inhibitor. PSI (TFA) inhibits the proliferation of primary effusion lymphoma (PEL) cells. PSI (TFA) can be used for the research of Kaposi’s sarcoma-associated herpesvirus (KSHV) infection and KSHV-associated lymphomas[1].
Product Name Alternative
Proteasome Inhibitor 1 (TFA) ; Z-Ile-Glu (OtBu) -Ala-Leu-CHO (TFA)
UNSPSC
12352209
Target
Proteasome
Type
Peptides
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/psi-tfa.html
Solubility
10 mM in DMSO
Smiles
OC(C(F)(F)F)=O.O=C([C@H]([C@@H](C)CC)NC(OCC1=CC=CC=C1)=O)N[C@@H](CCC(OC(C)(C)C)=O)C(N[C@@H](C)C(N[C@H](C=O)CC(C)C)=O)=O
Molecular Formula
C34H51F3N4O10
Molecular Weight
732.78
References & Citations
[1] Saji C, et al. Proteasome inhibitors induce apoptosis and reduce viral replication in primary effusion lymphoma cells. Biochem Biophys Res Commun. 2011; 415 (4) :573-8.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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