PSI-352938

• Description:

  PSI-352938 (PSI-938) is a hepatitis C virus (HCV) nucleotide inhibitor[1].

• Product Name Alternative:

  PSI-938

• UNSPSC:

  12352005

• Target:

  HCV

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/PSI-352938.html

• Solubility:

  10 mM in DMSO

• Smiles:

  F[C@]1(C)[C@H](O[P@]2(OC(C)C)=O)[C@@H](CO2)O[C@H]1N3C(N=C(N)N=C4OCC)=C4N=C3

• Molecular Formula:

  C16H23FN5O6P

• Molecular Weight:

  431.36

• References & Citations:

  [1]Lam AM, et al. Hepatitis C virus nucleotide inhibitors PSI-352938 and PSI-353661 exhibit a novel mechanism of resistance requiring multiple mutations within replicon RNA. J Virol. 2011 Dec;85 (23) :12334-42.|[2]Lam AM, et al. Inhibition of hepatitis C virus replicon RNA synthesis by PSI-352938, a cyclic phosphate prodrug of β-D-2'-deoxy-2'-α-fluoro-2'-β-C-methylguanosine. Antimicrob Agents Chemother. 2011 Jun;55 (6) :2566-75.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 1

• CAS Number:

  1199809-32-9