PSI-352938

CAT: 0804-HY-15231Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-15231Size:1 Each
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Description
PSI-352938 (PSI-938) is a hepatitis C virus (HCV) nucleotide inhibitor[1].
CAS Number
[1199809-32-9]
Product Name Alternative
PSI-938
UNSPSC
12352005
Target
HCV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/PSI-352938.html
Solubility
10 mM in DMSO
Smiles
F[C@]1(C)[C@H](O[P@]2(OC(C)C)=O)[C@@H](CO2)O[C@H]1N3C(N=C(N)N=C4OCC)=C4N=C3
Molecular Formula
C16H23FN5O6P
Molecular Weight
431.36
References & Citations
[1]Lam AM, et al. Hepatitis C virus nucleotide inhibitors PSI-352938 and PSI-353661 exhibit a novel mechanism of resistance requiring multiple mutations within replicon RNA. J Virol. 2011 Dec;85 (23) :12334-42.|[2]Lam AM, et al. Inhibition of hepatitis C virus replicon RNA synthesis by PSI-352938, a cyclic phosphate prodrug of β-D-2'-deoxy-2'-α-fluoro-2'-β-C-methylguanosine. Antimicrob Agents Chemother. 2011 Jun;55 (6) :2566-75.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1

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