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Recombinant Mouse Eotaxin (CCL11)

CAT: 0171-Z200039Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0171-Z200039Size:1 mg
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Description
Eotaxin belongs to the platelet factor-4 family of chemokines. The gene symbol is SCYA11. The factor is being referred to also as Eotaxin-1 and has been renamed CCL11. Eotaxin induces substantial accumulation of eosinophils in the skin without significantly affecting the accumulation of neutrophils. Eotaxin is a potent stimulator of both guinea pig and human eosinophils in vitro. The Eotaxin receptor is a G-protein-coupled receptor selectively expressed in human eosinophils.
CAS Number
9000-83-3
Gene Name
CCL11
Gene Aliases
C-C motif chemokine 11, Eosinophil chemotactic protein, Small-inducible cytokine A11, SCYA11
Gene ID
20292
Accession Number
P48298
Organism
Mouse
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Function
Activity was determined by the ability to chemoattract human peripheral blood eosinophils using a concentration range of 0.1-20 ng/mL.
Molecular Weight
8
Shipping Conditions
Ambient Temperature
Storage Conditions
The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Appearance
Lyophilized Powder
Formulation
Recombinant mouse Eotaxin was lyophilized from a 0.2 μm filtered PBS solution.

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