Succinate dehydrogenase-IN-1

Succinate dehydrogenase-IN-1

• CAS Number: 2969128-94-5
• UNSPSC Description: Succinate dehydrogenase-IN-1 (Compound 34) is an inhibitor for succinate dehydrogenase (SDH) with an IC50 of 0.94 μM and a KD of 22.4 μM. Succinate dehydrogenase-IN-1 exhibits antifungal activity against Rhizoctonia solani, Sclerotinia sclerotiorum, Monilinia fructicola, and Botrytis cinerea, with EC50 of 0.04 μM, 1.13 μM, 1.61 μM and 1.21 μM, respectively[1].
• Target Antigen: Fungal
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/succinate-dehydrogenase-in-1.html
• Smiles: O=C(C1=CN(C)N=C1C(F)F)NC2=CC=CC=C2/C(F)=C/C3=CC(F)=C(F)C(F)=C3
• Molecular Weight: 425.33
• References & Citations: [1]Chen Y, et al., Design, Synthesis, and Antifungal Activities of Novel Potent Fluoroalkenyl Succinate Dehydrogenase Inhibitors. J Agric Food Chem. 2024 Jul 3;72(26):14535-14546.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported