Succinate dehydrogenase-IN-2

• UNSPSC Description:

  Succinate dehydrogenase-IN-2 (Compound 12x) is an inhibitor for succinate dehydrogenase (SDH) with an IC50 of 1.22 mg/L. Succinate dehydrogenase-IN-2 exhibits antifungal activity, that inhibits S. sclerotiorum, V. mali, G. graminis, R. solani and B. cinerea with EC50 of 0.52-3.42 mg/L[1].

• Target Antigen:

  Parasite; Succinate Dehydrogenase

• Type:

  Reference compound

• Related Pathways:

  Anti-infection;Metabolic Enzyme/Protease

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/succinate-dehydrogenase-in-2.html

• Smiles:

  O=C(C1=C(OC2=CC(Cl)=CC(Cl)=C2)C=CC=C1)NC3=C(C(C(F)(F)F)=NN3C)F

• Molecular Weight:

  448.20

• References & Citations:

  [1]Xu D, et al., Discovery, Optimization, and Biological Evaluation of Novel Pyrazol-5-yl-phenoxybenzamide Derivatives as Potent Succinate Dehydrogenase Inhibitors. J Agric Food Chem. 2024 Jul 24.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Phase 1

• CAS Number:

  3023681-83-3