DMT-dC(bz) Phosphoramidite-13C9,15N3

• UNSPSC Description:

  DMT-dC(bz) Phosphoramidite-13C9,15N3 is the 13C and 15N labeled DMT-dC(bz) Phosphoramidite[1]. DMT-dC(bz) Phosphoramidite is typically used in the synthesis of DNA[2].

• Target Antigen:

  DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/dmt-dc-bz-phosphoramidite-13c9-15n3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(N(P(O[13C@H]1[13CH2][13C@@]([H])(O[13C@@H]1[13CH2]OC(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)[15N]5[13C]([15N]=[13C]([15NH]C(C6=CC=CC=C6)=O)[13CH]=[13CH]5)=O)OCCC#N)C(C)C)C

• Molecular Weight:

  845.82

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]James D Thorpe, et al. Mechanochemical Synthesis of Short DNA Fragments. Chemistry. 2020 Jul 22;26(41):8857-8861.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2483830-14-2