Ac-rC Phosphoramidite-13C9,15N3

Ac-rC Phosphoramidite-13C9,15N3

• UNSPSC Description: Ac-rC Phosphoramidite-13C9,15N3 is 13C and 15N-labeled Ac-rC Phosphoramidite (HY-W042357). Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA).
• Target Antigen: DNA/RNA Synthesis; Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Cell Cycle/DNA Damage;Others
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/ac-rc-phosphoramidite-13c9-15n3.html
• Solubility: 10 mM in DMSO
• Smiles: COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)O[13CH2][13C@@H]4[13C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[13C@@H](O[Si](C)(C)C(C)(C)C)[13C@H]([15N]5[13C]([15N]=[13C]([15NH]C(C)=O)[13CH]=[13CH]5)=O)O4
• Molecular Weight: 914.01
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Wipapat Kladwang, et al. Anomalous Reverse Transcription through Chemical Modifications in Polyadenosine Stretches. Biochemistry. 2020 Jun 16;59(23):2154-2170.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported