DMT-2'-F-dC(Bz)-CE-Phosphoramidite

DMT-2'-F-dC(Bz)-CE-Phosphoramidite

• CAS Number: 182495-83-6
• UNSPSC Description: DMT-2'-F-dC(Bz)-CE-Phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/dmt-2-f-dc-bz-ce-phosphoramidite.html
• Solubility: 10 mM in DMSO
• Smiles: COC(C=C1)=CC=C1C(C2=CC=C(C=C2)OC)(C3=CC=CC=C3)OC[C@@H]4[C@@H](COP(OCCC#N)N(C(C)C)C(C)C)[C@@H](F)[C@H](N5C(N=C(C(C)=C5)NC(C6=CC=CC=C6)=O)=O)O4
• Molecular Weight: 879.95
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported