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(E/Z) -4-Hydroxytamoxifen (Standard)

CAT: 0804-HY-16950AR-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-16950AR-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(E/Z) -4-Hydroxytamoxifen (Standard) is the analytical standard of (E/Z) -4-Hydroxytamoxifen. This product is intended for research and analytical applications. (E/Z) -4-Hydroxytamoxifen (Afimoxifene) is a racemic compound of (Z) -4-Hydroxytamoxifen and (E) -4-Hydroxytamoxifen isomers. (E/Z) -4-Hydroxytamoxifen is a selective estrogen receptor modulator with mixed estrogenic and antiestrogenic activity, which is also an active metabolite of Tamoxifen. (E/Z) -4-Hydroxytamoxifen is an agonist of the G protein-coupled estrogen receptor (GPER) with relatively low affinity (100-1000 nM). (E/Z) -4-Hydroxytamoxifen is promising for research of cyclical mastalgia, such as breast pain, tenderness, and nodularity[1][2][3][4].
CAS Number
68392-35-8
Product Name Alternative
Afimoxifene (Standard) ; 4-OHT (Standard)
UNSPSC
12352005
Target
Endogenous Metabolite; Estrogen Receptor/ERR; Reference Standards
Type
Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/e-z-4-hydroxytamoxifen-standard.html
Smiles
OC1=CC=C(/C(C2=CC=C(OCCN(C)C)C=C2)=C(C3=CC=CC=C3)\CC)C=C1
Molecular Formula
C26H29NO2
Molecular Weight
387.51
Shipping Conditions
Room temperature
Scientific Category
Reference Standards