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Anticancer agent 213

CAT: 0804-HY-158373Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-158373Size:1 Each
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Description
Anticancer agent 213 (Compound 1) exhibits anticancer efficacy by self-assembling into micelles, depleting membran cholesterol and thus inhibiting cancer cells. Anticancer agent 213 exhibits cytotoxicity against HeLa and PC3, with IC50 of 10.3 and 13.7 μM. Anticancer agent 213 induces autophagy[1].
CAS Number
9007-83-4
UNSPSC
12352005
Target
Autophagy
Type
Reference compound
Related Pathways
Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-213.html
Solubility
10 mM in DMSO
Smiles
N[C@@H](C(N[C@@H](C(NCCNC1=CC=C(C2=NON=C12)[N+]([O-])=O)=O)CC3=CC=C(C=C3)C4=CC=CC=C4)=O)CC5=CC=C(C=C5)C6=CC=CC=C6
Molecular Formula
C38H35N7O5
Molecular Weight
669.73
References & Citations
[1]Zhang Q, et al., Unnatural Peptide Assemblies Rapidly Deplete Cholesterol and Potently Inhibit Cancer Cells. J Am Chem Soc. 2024 May 15;146 (19) :12901-12906.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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