Anticancer agent 213

• UNSPSC Description:

  Anticancer agent 213 (Compound 1) exhibits anticancer efficacy by self-assembling into micelles, depleting membran cholesterol and thus inhibiting cancer cells. Anticancer agent 213 exhibits cytotoxicity against HeLa and PC3, with IC50 of 10.3 and 13.7 μM. Anticancer agent 213 induces autophagy[1].

• Target Antigen:

  Autophagy

• Type:

  Reference compound

• Related Pathways:

  Autophagy

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/anticancer-agent-213.html

• Solubility:

  10 mM in DMSO

• Smiles:

  N[C@@H](C(N[C@@H](C(NCCNC1=CC=C(C2=NON=C12)[N+]([O-])=O)=O)CC3=CC=C(C=C3)C4=CC=CC=C4)=O)CC5=CC=C(C=C5)C6=CC=CC=C6

• Molecular Weight:

  669.73

• References & Citations:

  [1]Zhang Q, et al., Unnatural Peptide Assemblies Rapidly Deplete Cholesterol and Potently Inhibit Cancer Cells. J Am Chem Soc. 2024 May 15;146(19):12901-12906.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4