HIF-IN-1
CAT:
804-HY-146144-04
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
HIF-IN-1
- CAS Number: 2393928-76-0
- UNSPSC Description: HIF-IN-1 (Compound 3c) is a hypoxia-inducible factor (HIF)-1 inhibitor. HIF-IN-1 suppresses HIF-1α protein accumulation without affecting the levels of HIF-1α mRNA. HIF-IN-1 shows no obvious cytotoxicity[1].
- Target Antigen: HIF/HIF Prolyl-Hydroxylase
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/hif-in-1.html
- Solubility: DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: O=C(C1=C2C=NN1C3=CC=C(C)C=C3)C4=C2C=CC=C4
- Molecular Weight: 260.29
- References & Citations: [1]Fuse S, et al. Design, synthesis, and evaluation of indeno[2,1-c]pyrazolones for use as inhibitors against hypoxia-inducible factor (HIF)-1 transcriptional activity. Bioorg Med Chem. 2020 Jan 1;28(1):115207.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported