HIF-1α-IN-3
CAT:
804-HY-147813
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

HIF-1α-IN-3
- CAS Number: 2170715-64-5
- UNSPSC Description: HIF-1α-IN-3 (Compound (S)-3f) is a hypoxia-selective HIF-1α inhibitor. HIF-1α-IN-3 shows strong antiestrogenic potency[1].
- Target Antigen: HIF/HIF Prolyl-Hydroxylase
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/hif-1α-in-3.html
- Solubility: 10 mM in DMSO
- Smiles: N#CC1=C(C2=CC=CC=C2)[N+]([O-])=C3C=CC(N4C[C@@H](N)CC4)=CC3=[N+]1[O-]
- Molecular Weight: 347.37
- References & Citations: [1]Buravchenko GI, et al. Discovery of derivatives of 6(7)-amino-3-phenylquinoxaline-2-carbonitrile 1,4-dioxides: novel, hypoxia-selective HIF-1α inhibitors with strong antiestrogenic potency. Bioorg Chem. 2020 Nov;104:104324.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported