Products for Research Use Only
RegisterLogin

POSH-IN-1

CAT: 0804-HY-165161-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-165161-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
POSH-IN-1 (Compound 108) is an inhibitor for POSH polypeptide, that inhibits the ubiquitin ligase of POSH with an IC50 of 900 nM[1].
CAS Number
328960-84-5
UNSPSC
12352005
Target
HIV
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/posh-in-1.html
Purity
99.71
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1S/C(C(N1)=O)=C\C2=CC=C(C3=CC=C(F)C=C3)O2
Molecular Formula
C14H8FNO3S
Molecular Weight
289.28
References & Citations
[1]Alroy I, et al., Ubiquitin ligase inhibitors and methods related thereto. WO2005007141.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

5-[[5-(4-Fluorophenyl)furan-2-yl]methylidene]-1,3-thiazolidine-2,4-dione
CAS Number328960-84-5
PubChem CID2844288
IUPAC Name5-[[5-(4-fluorophenyl)furan-2-yl]methylidene]-1,3-thiazolidine-2,4-dione
Molecular FormulaC14H8FNO3S
Molecular Weight289.28
XLogP3.1
Topological Polar Surface Area84.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Heavy Atom Count20
Formal Charge0
Complexity446
SMILES
C1=CC(=CC=C1C2=CC=C(O2)C=C3C(=O)NC(=O)S3)F
InChI
InChI=1S/C14H8FNO3S/c15-9-3-1-8(2-4-9)11-6-5-10(19-11)7-12-13(17)16-14(18)20-12/h1-7H,(H,16,17,18)
InChIKey
UFBTYTGRUBUUIL-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 5-[[5-(4-Fluorophenyl)furan-2-yl]methylidene]-1,3-thiazolidine-2,4-dione
CAS: 328960-84-5
CID: 2844288
Formula: C14H8FNO3S
MW: 289.28
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight289.28
XLogP33.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Exact Mass289.02089245
Monoisotopic Mass289.02089245
Topological Polar Surface Area84.6 Ų
Heavy Atom Count20
Formal Charge0
Complexity446
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count1
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-164566-01POSH-IN-2
HY-157154-01MAT-POS-e194df51-1
HY-N6838-011,1,1,1-Kestohexaose
HY-157129AMPK-α1β1γ1 activator 1
HY-1336231,1,1-Tribromoacetone
HY-149536TWIK-1/TREK-1-IN-1
HY-W160628S1,1,1-Trimethoxypropane-d5
HY-133630-011-Bromo-1,1-dichloroacetone
HY-1336291,1,1,3-Tetrachloroacetone
HY-W881439-011- (1,1-Dimethylethyl) tridecanedioate

Alternative Products

CatalogName
BUP21122-01POSH-IN-1
sc-390103POSH (E-1)
sc-390103 PPOSH (E-1) P
sc-390103 FITCPOSH (E-1) FITC
C48490-01POSH Antibody
GTR19238884-01POSH-IN-2
sc-390103 ACPOSH (E-1) AC
sc-390103 PEPOSH (E-1) PE
sc-390103 HRPPOSH (E-1) HRP
512992POSH discontinued

Popular Products