(E/Z)-HA155

• Product Name Alternative:

  KPT-8602

• UNSPSC Description:

  (E/Z)-HA155 is a potent autotaxin (ATX) type I inhibitor. (E/Z)-HA155 can be used for researching cancer, fibrotic diseases, inflammation, pain and angiogenesis[1].

• Target Antigen:

  Phosphodiesterase (PDE)

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Cancer; Inflammation/Immunology; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/e-z-ha155.html

• Purity:

  99.26

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)

• Smiles:

  OB(O)C1=CC=C(C=C1)COC2=CC=C(C=C2)/C=C(C3=O)\SC(N3CC4=CC=C(C=C4)F)=O

• Molecular Weight:

  463.29

• References & Citations:

  [1]Joncour A, et al. Discovery, Structure-Activity Relationship, and Binding Mode of an Imidazo[1,2-a]pyridine Series of Autotaxin Inhibitors [published correction appears in J Med Chem. 2018 May 10;61(9):4270]. J Med Chem. 2017;60(17):7371-7392.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  1229652-22-5