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Ganoderic acid B

CAT: 0804-HY-N2006-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N2006-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ganoderic acid B is a triterpene isolated from a mushroom Ganoderma lucidum. Ganoderic acid B inhibits the activation of Epstein-Barr virus (EBV) antigens as telomerase inhibitor. Ganoderic acid B is a moderately active inhibitor against HIV-1 protease (IC50: 170 μM) [1][2][3].
CAS Number
81907-61-1
UNSPSC
12352211
Target
EBV; HIV Protease
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ganoderic-acid-b.html
Purity
99.60
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
C[C@]([C@@]([C@]([C@H](C)CC(C[C@@H](C)C(O)=O)=O)([H])C1)(CC2=O)C)(C1=O)C([C@H](C[C@@]3([H])C4(C)C)O)=C2[C@]3(CC[C@@H]4O)C
Molecular Formula
C30H44O7
Molecular Weight
516.67
References & Citations
[1]Zhou S, et al. Triterpenes and Soluble Polysaccharide Changes in Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), During Fruiting Growth. Int J Med Mushrooms. 2018;20 (9) :859-871.|[2]Zheng DS, et al. Triterpenoids from Ganoderma lucidum inhibit the activation of EBV antigens as telomerase inhibitors. Exp Ther Med. 2017 Oct;14 (4) :3273-3278.|[3]el-Mekkawy S, et al. Anti-HIV-1 and anti-HIV-1-protease substances from Ganoderma lucidum. Phytochemistry. 1998 Nov;49 (6) :1651-7.|[4]Shi J, et al. Ganoderic acid B attenuates LPS-induced lung injury. Int Immunopharmacol. 2020 Nov;88:106990.|[5]Koyama K, et al. Antinociceptive components of Ganoderma lucidum. Planta Med. 1997 Jun;63 (3) :224-7.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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