Ganoderic acid H

• Description:

  Ganoderic acid H is a lanostane-type triterpene isolated from Ganoderma lucidum. Ganoderic acid H suppresses growth and invasive behavior of breast cancer cells through the inhibition of transcription factors AP-1 and NF-kappaB signaling[1].

• UNSPSC:

  12352211

• Target:

  AP-1; NF-κB

• Type:

  Natural Products

• Related Pathways:

  Immunology/Inflammation; NF-κB

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ganoderic-acid-h.html

• Purity:

  99.25

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CC(C)(C1C2)C(O)CCC1(C)C3=C(C4(C(CC(C4(C(OC(C)=O)C3=O)C)C(C)CC(CC(C)C(O)=O)=O)=O)C)C2=O

• Molecular Formula:

  C32H44O9

• Molecular Weight:

  572.69

• References & Citations:

  [1]Jiang J, et al. Ganoderic acids suppress growth and invasive behavior of breast cancer cells by modulating AP-1 and NF-kappaB signaling. Int J Mol Med. 2008 May;21 (5) :577-84.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  [98665-19-1]