Genistein-d4
CAT:
804-HY-14596S-02
Size:
5 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Genistein-d4
- CAS Number: 187960-08-3
- UNSPSC Description: Genistein-d4 is the deuterium labeled Genistein. Genistein, a soy isoflavone, is a multiple tyrosine kinases (e.g., EGFR) inhibitor which acts as a chemotherapeutic agent against different types of cancer, mainly by altering apoptosis, the cell cycle, and angiogenesis and inhibiting metastasis[1][2].
- Target Antigen: Apoptosis; Autophagy; EGFR; Endogenous Metabolite
- Type: Isotope-Labeled Compounds
- Related Pathways: Apoptosis;Autophagy;JAK/STAT Signaling;Metabolic Enzyme/Protease;Protein Tyrosine Kinase/RTK
- Field of Research: Cancer
- Solubility: DMSO : 50 mg/mL (ultrasonic)
- Smiles: O=C1C(C2=C(C([2H])=C(C([2H])=C2[2H])O)[2H])=COC3=CC(O)=CC(O)=C31
- Molecular Weight: 274.26
- References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Peterson G, et al. Genistein inhibits both estrogen and growth factor-stimulated proliferation of human breast cancer cells. Cell Growth Differ. 1996 Oct;7(10):1345-51.|[3]Ding S, et al. Environmentally Relevant Dose of Bisphenol A Does Not Affect Lipid Metabolism and Has No Synergetic or Antagonistic Effects on Genistein's Beneficial Roles on Lipid Metabolism. PLoS One. 2016 May 12;11(5):e0155352.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported