Genistein
CAT:
804-HY-14596-01
Size:
100 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Genistein
- CAS Number: 446-72-0
- UNSPSC Description: Genistein, a soy isoflavone, is a multiple tyrosine kinases (e.g., EGFR) inhibitor which acts as a chemotherapeutic agent against different types of cancer, mainly by altering apoptosis, the cell cycle, and angiogenesis and inhibiting metastasis.
- Target Antigen: Apoptosis; Autophagy; EGFR; Endogenous Metabolite
- Type: Natural Products
- Related Pathways: Apoptosis;Autophagy;JAK/STAT Signaling;Metabolic Enzyme/Protease;Protein Tyrosine Kinase/RTK
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/Genistein.html
- Solubility: DMSO : ≥ 100 mg/mL|H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)
- Smiles: OC1=C2C(OC=C(C3=CC=C(O)C=C3)C2=O)=CC(O)=C1
- Molecular Weight: 270.24
- References & Citations: [1]Peterson G, et al. Genistein inhibits both estrogen and growth factor-stimulated proliferation of human breast cancer cells. Cell Growth Differ. 1996 Oct;7(10):1345-51.|[2]Ding S, et al. Environmentally Relevant Dose of Bisphenol A Does Not Affect Lipid Metabolism and Has No Synergetic or Antagonistic Effects on Genistein's Beneficial Roles on Lipid Metabolism. PLoS One. 2016 May 12;11(5):e0155352.
- Shipping Conditions: Room Temperature
- Clinical Information: Phase 4