Pyrithione

Pyrithione

• CAS Number: 1121-30-8
• UNSPSC Description: Pyrithione, a Transition metal complexe, is a zinc ionophore that causes increased zinc levels within mammalian cells. Pyrithione has potent bactericidal and anti-fungal activity[1][2].
• Target Antigen: Bacterial; Fungal
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/pyrithione.html
• Purity: 99.75
• Solubility: DMSO : 125 mg/mL (ultrasonic)
• Smiles: S=C1C=CC=CN1O
• Molecular Weight: 127.16
• References & Citations: [1]PANSY FE, et al. In vitro studies with 1-hydroxy-2(1H) pyridinethione. Proc Soc Exp Biol Med. 1953 Jan;82(1):122-4.|[2]Nancy L Reeder, et al. Zinc pyrithione inhibits yeast growth through copper influx and inactivation of iron-sulfur proteins. Antimicrob Agents Chemother. 2011 Dec;55(12):5753-60.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported