Zinc Pyrithione
CAT:
804-HY-B0572-02
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Zinc Pyrithione
- CAS Number: 13463-41-7
- UNSPSC Description: Zinc Pyrithione is an antifungal and antibacterial agent disrupting membrane transport by blocking the proton pump[1]. Zinc Pyrithione is also a copper ionophore that delivers copper into cells and is a useful tool for studying cuproptosis[2].
- Target Antigen: Bacterial; Cuproptosis; Fungal; Proton Pump
- Type: Reference compound
- Related Pathways: Anti-infection;Apoptosis;Membrane Transporter/Ion Channel
- Applications: COVID-19-anti-virus
- Field of Research: Infection; Metabolic Disease
- Assay Protocol: https://www.medchemexpress.com/zinc-pyrithione.html
- Purity: 99.49
- Solubility: DMSO : 33.33 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL
- Smiles: N12[O-][Zn+2]3([S]=C1C=CC=C2)[O-]N(C=CC=C4)C4=[S]3
- Molecular Weight: 317.69
- References & Citations: [1]Ermolayeva, E. and D. Sanders, Mechanism of pyrithione-induced membrane depolarization in Neurospora crassa. Appl Environ Microbiol, 1995. 61(9): p. 3385-90.|[2]Peter Tsvetkov, et al. Copper induces cell death by targeting lipoylated TCA cycle proteins. Science. 2022 Mar 18;375(6586):1254-1261.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: Launched