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DCB-3503

CAT: 0804-HY-111244Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-111244Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DCB-3503 is an allosteric modulator of heat shock cognate protein HSC70 and an inhibitor of Cyclin D1. DCB-3503 inhibits Cyclin D1 translation by allosterically modulating the ATPase and chaperone activities of HSC70. DCB-3503 may inhibit malignancies such as hepatocellular carcinoma or breast cancer with elevated expression of cyclin D1[1].
CAS Number
87302-58-7
UNSPSC
12352005
Target
CDK; HSP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/dcb-3503.html
Smiles
O[C@H]1C2=C(C=C(C(OC)=C3)OC)C3=C(C=C(C(OC)=C4)OC)C4=C2CN5[C@@]1([H])CCC5
Molecular Formula
C24H27NO5
Molecular Weight
409.47
References & Citations
[1]Tylophorine Analog DCB-3503 Inhibited Cyclin D1 Translation through Allosteric Regulation of Heat Shock Cognate Protein 70
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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