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DCB-3503

CAT: 0931-T27128-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T27128-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
87302-58-7
Target
Others, HSP, CDK
Related Pathways
Metabolism, Cytoskeletal Signaling, Cell Cycle/Checkpoint, Others
Bioactivity
Tylophorine analog DCB-3503 is a potential anticancer and immunosuppressive agent. DCB-3503 suppresses the translation of cellular regulatory proteins, including cyclin D1, at the elongation step. DCB-3503 allosterically regulates the ATPase and chaperone activities of HSC70 by promoting ATP hydrolysis in the presence of specific RNA binding motifs (AUUUA) of cyclin D1 mRNA.
Smiles
O[C@H]1C=2C(=C3C(=C4C2C=C(OC)C(OC)=C4)C=C(OC)C(OC)=C3)CN5[C@]1(CCC5)[H]
Molecular Formula
C24H27NO5
Molecular Weight
409.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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