DCB-3503

• Target :

  Others|||HSP|||CDK

• Related Pathways :

  Metabolism|||Cytoskeletal Signaling|||Cell Cycle/Checkpoint|||Others

• Bioactivity :

  Tylophorine analog DCB-3503 is a potential anticancer and immunosuppressive agent. DCB-3503 suppresses the translation of cellular regulatory proteins, including cyclin D1, at the elongation step. DCB-3503 allosterically regulates the ATPase and chaperone activities of HSC70 by promoting ATP hydrolysis in the presence of specific RNA binding motifs (AUUUA) of cyclin D1 mRNA.

• Smiles :

  O[C@H]1C=2C(=C3C(=C4C2C=C(OC)C(OC)=C4)C=C(OC)C(OC)=C3)CN5[C@]1(CCC5)[H]

• Molecular Formula :

  C24H27NO5

• Molecular Weight :

  409.47

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  87302-58-7