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Tramiprosate (Standard)

CAT: 0804-HY-14602R-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-14602R-01Size:10 mg
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Description
Tramiprosate (Standard) is the analytical standard of Tramiprosate. This product is intended for research and analytical applications. Tramiprosate (Homotaurine), an orally active and brain-penetrant natural amino acid found in various species of red marine algae. Tramiprosate binds to soluble Aβ and maintains Aβ in a non-fibrillar form. Tramiprosate is also a GABA analog and possess neuroprotection, anticonvulsion and antihypertension effects[1][2][3].
CAS Number
3687-18-1
Product Name Alternative
Homotaurine (Standard) ; 3-Amino-1-propanesulfonic acid (Standard)
UNSPSC
12352211
Target
Amyloid-β; Reference Standards
Type
Reference Standards
Related Pathways
Neuronal Signaling; Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tramiprosate-standard.html
Smiles
NCCCS(=O)(O)=O
Molecular Formula
C3H9NO3S
Molecular Weight
139.17
References & Citations
[1]Wu S et al. Tramiprosate protects neurons against ischemic stroke by disrupting the interaction between PSD95 and nNOS. Neuropharmacology. 2014 Aug;83:107-17.|[2]Francine Gervais, et al. Targeting soluble Abeta peptide with Tramiprosate for the treatment of brain amyloidosis. Neurobiol Aging. 2007 Apr;28 (4) :537-47.|[3]R G Fariello, et al. Homotaurine (3 aminopropanesulfonic acid; 3APS) protects from the convulsant and cytotoxic effect of systemically administered kainic acid. Neurology. 1982 Mar;32 (3) :241-5.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

Chemical Information

Tramiprosate

3-aminopropanesulfonic acid is an amino sulfonic acid that is the 3-amino derivative of propanesulfonic acid. It has a role as an anticonvulsant, a GABA agonist, a nootropic agent, an anti-inflammatory agent and an algal metabolite. It is a tautomer of a 3-aminopropanesulfonic acid zwitterion.

CAS Number3687-18-1
PubChem CID1646
IUPAC Name3-aminopropane-1-sulfonic acid
Molecular FormulaC3H9NO3S
Molecular Weight139.18
XLogP-3.8
Topological Polar Surface Area88.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Heavy Atom Count8
Formal Charge0
Complexity133
SMILES
C(CN)CS(=O)(=O)O
InChI
InChI=1S/C3H9NO3S/c4-2-1-3-8(5,6)7/h1-4H2,(H,5,6,7)
InChIKey
SNKZJIOFVMKAOJ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Tramiprosate
CAS: 3687-18-1
CID: 1646
Formula: C3H9NO3S
MW: 139.18
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight139.18
XLogP3-3.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass139.03031432
Monoisotopic Mass139.03031432
Topological Polar Surface Area88.8 Ų
Heavy Atom Count8
Formal Charge0
Complexity133
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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