Products for Research Use Only
RegisterLogin

UBP20 rabbit pAb

CAT: 0855-ES12446-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES12446-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene encodes a ubiquitin specific processing protease that was first identified as a substrate of the VHL (von Hippel-Lindau disease) protein E3 ubiquitin ligase complex. In addition to being ubiquitinated by the VHL-E3 ligase complex, this enzyme deubiquitinates hypoxia-inducible factor (HIF) -1 alpha and thereby causes increased expression of HIF-1alpha targeted genes which play a role in angiogenesis, glucose metabolism, cell proliferation and metastasis. The enzyme encoded by this gene also regulates G-protein coupled receptor signaling by mediating the deubiquitination of beta-2 adrenergic receptor (ADRB2) . This enzyme is a ubiquitously expressed thiolester hydrolase. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jan 2013]
Description
This gene encodes a ubiquitin specific processing protease that was first identified as a substrate of the VHL (von Hippel-Lindau disease) protein E3 ubiquitin ligase complex. In addition to being ubiquitinated by the VHL-E3 ligase complex, this enzyme deubiquitinates hypoxia-inducible factor (HIF)-1 alpha and thereby causes increased expression of HIF-1alpha targeted genes which play a role in angiogenesis, glucose metabolism, cell proliferation and metastasis. The enzyme encoded by this gene also regulates G-protein coupled receptor signaling by mediating the deubiquitination of beta-2 adrenergic receptor (ADRB2). This enzyme is a ubiquitously expressed thiolester hydrolase. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jan 2013],
UniProt
Q9Y2K6
Swiss Prot
Q9Y2K6
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human UBP20 AA range: 104-154
Target
UBP20
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Cytoplasm, perinuclear region . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . According to PubMed:12865408, it localizes in the endoplasmic reticulum; however the relevance of such result is unclear.
Gene ID (Human)
10868

Related Products

CatalogName
ES12444-01UBP25 rabbit pAb
ES12445-01UBP21 rabbit pAb
ES10415-01UBP29 rabbit pAb
ES10410-01UBP10 rabbit pAb
ES10414-01UBP26 rabbit pAb
ES19300-01UBP2 rabbit pAb
ES4666-01RAB3IP rabbit pAb
ES20751-01Gab1 Rabbit rabbit pAb
ES20703-01JAK2 Rabbit rabbit pAb
ES20758-01ERK1 Rabbit rabbit pAb

Alternative Products

CatalogName
E28PN3789UBP20 rabbit pAb
BT-AP13344-01UBP20 Rabbit Polyclonal Antibody
GTR18401606-01UBP20 rabbit pAb Antibody
WP4153-01U-Blot® UBP20 rabbit pAb
PAV4233Rabbit Anti-UBP20/USP20 Polyclonal Antibody
MBS9010024Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) UBP20 Polyclonal Antibody
GTR17961640UBP20 Antibody
E106366Mouse UBP20 ELISA Kit
MBS1403420Recombinant Arabidopsis thaliana Ubiquitin carboxyl-terminal hydrolase 20 (UBP20) , partial
U4101USP20 (UBP20, USP-20, UBP-20, Ubiquitin Specific Peptidase 20, VDU2, VDU-2, pVHL-interacting Deubiquitinating Enzyme 2) discontinued

Popular Products