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UBP21 rabbit pAb

CAT: 0855-ES12445-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES12445-01Size:50 µL
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Background
This gene encodes a member of the C19 peptidase family, also known as family 2 of ubiquitin carboxy-terminal hydrolases. The encoded protein cleaves ubiquitin from ubiquitinated proteins for recycling in intracellular protein degradation. The encoded protein is also able to release NEDD8, a ubiquitin-like protein, from NEDD8-conjugated proteins. This gene has been referred to as USP16 and USP23 but is now known as USP21. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]
Description
This gene encodes a member of the C19 peptidase family, also known as family 2 of ubiquitin carboxy-terminal hydrolases. The encoded protein cleaves ubiquitin from ubiquitinated proteins for recycling in intracellular protein degradation. The encoded protein is also able to release NEDD8, a ubiquitin-like protein, from NEDD8-conjugated proteins. This gene has been referred to as USP16 and USP23 but is now known as USP21. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016],
Product Name Alternative
Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.4.19.12) (Deubiquitinating enzyme 21) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21)
UniProt
Q9UK80
Swiss Prot
Q9UK80
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human UBP21 AA range: 50-100
Target
UBP21
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Molecular Weight
60kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
60kD
Fragment
IgG
Subcellular Location
Cytoplasm . Nucleus .
Other Product Names
Ubiquitin carboxyl-terminal hydrolase 21 (EC 3.4.19.12) (Deubiquitinating enzyme 21) (Ubiquitin thioesterase 21) (Ubiquitin-specific-processing protease 21)
Gene ID (Human)
27005

UniProtKB · Q9UK80

Ubiquitin carboxyl-terminal hydrolase 21

UBP21_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UK80
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
USP21
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.19.12
Processing
—
Secondary accessions
Q59H60, Q5BKT5, Q5VTW9, Q5VTX0, Q9BTV1, Q9HBS2, Q9NYN4
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

ActivatorChromatin regulatorHydrolaseProteaseThiol protease

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmNucleus

Ligand

Metal-bindingZinc

Biological process

TranscriptionTranscription regulationUbl conjugation pathway

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