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NLRC4 rabbit pAb

CAT: 0855-ES14480-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES14480-01Size:50 µL
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Background
This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
Description
This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014],
UniProt
Q9NPP4
Swiss Prot
Q9NPP4
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human NLRC4 AA range: 481-531
Target
NLRC4
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Cytoplasm . Cytoplasm, cytosol . Inflammasome .
Gene ID (Human)
58484

UniProtKB · Q9NPP4

NLR family CARD domain-containing protein 4

NLRC4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9NPP4
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NLRC4
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K9F8, B2RBQ3, B3KTF0, D6W580, Q96J81, Q96J82, Q96J83
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisImmunityInflammatory responseInnate immunity

Ligand

ATP-bindingNucleotide-binding

Cellular component

CytoplasmInflammasome

Disease

Disease variant

Domain

Leucine-rich repeatRepeat

PTM

Phosphoprotein

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