(R)-eIF4A3-IN-2
CAT:
804-HY-43913-04
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
(R)-eIF4A3-IN-2
- CAS Number: 2095484-82-3
- UNSPSC Description: (R)-eIF4A3-IN-2 is a less active enantiomer of eIF4A3-IN-2. eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 (eIF4A3) inhibitor with an IC50 of 110 nM[1].
- Target Antigen: Eukaryotic Initiation Factor (eIF)
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage
- Field of Research: Others
- Assay Protocol: https://www.medchemexpress.com/r-eif4a3-in-2.html
- Purity: 95.0
- Solubility: DMSO : 50 mg/mL (ultrasonic)
- Smiles: O=C(N1C[C@@H](C2=CC=C(Cl)C=C2)N(C(C3=CC=C(Br)C=C3)=O)CC1)C4=C5C=CC(Br)=CN5N=C4
- Molecular Weight: 602.70
- References & Citations: [1]Iwatani-Yoshihara M, et al. Discovery and Characterization of a Eukaryotic Initiation Factor 4A-3-Selective Inhibitor That Suppresses Nonsense-Mediated mRNA Decay. ACS Chem Biol. 2017;12(7):1760-1768.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported