Rofleponide epimer

• Description:

  Rofleponide epimer is a compound with anti-inflammatory activity. Rofleponide epimer has shown high selectivity in the lungs in experiments. Rofleponide epimer exhibits excellent pharmacological properties by efficiently binding to the rat thymic glucocorticoid receptor. The biotransformation rate of Rofleponide epimer is 10 times higher than that of other known similar drugs, indicating that it has potential application value in inhibiting inflammatory diseases involving mucosa[1].

• UNSPSC:

  12352005

• Target:

  Endogenous Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/rofleponide-epimer.html

• Smiles:

  OCC ([C@]12[C@@]3 ([C@@] ([C@@]4 ([H]) [C@] ([C@H] (C3) O) ([C@@]5 (C ([C@H] (C4) F) =CC (CC5) =O) C) F) ([H]) C[C@@]1 ([H]) O[C@@H] (O2) CCC) C) =O

• Molecular Formula:

  C25H34F2O6

• Molecular Weight:

  468.53

• References & Citations:

  [1]6 alpha-Fluoro- and 6 alpha,9 alpha-difluoro-11 beta,21-dihydroxy-16 alpha,17 alpha-propylmethylenedioxypregn-4-ene-3,20-dione: synthesis and evaluation of activity and kinetics of their C-22 epimers

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  144459-71-2