Tacrolimus 8-epimer

• Description :

  Tacrolimus anhydrous 8-epimer (Tacrolimus EP impurity D) is a l-pipecolic acid macrolide lactone, an important immunosuppressive agent that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2[1].

• Product Name Alternative :

  Tacrolimus EP impurity D; 8-epi-Tacrolimus

• UNSPSC :

  12352005

• Hazard Statement :

  H301

• Target :

  Phosphatase

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Purity :

  96.64

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  CO[C@@H]1[C@]2([H])O[C@]([C@@H](C1)C)(C(C(N3[C@](CCCC3)([H])C(O[C@@H]([C@@H]([C@H](CC([C@H](/C=C(C[C@@H](C[C@@H]2OC)C)\C)CC=C)=O)O)C)/C(C)=C/[C@H]4C[C@H]([C@@H](CC4)O)OC)=O)=O)=O)O

• Molecular Formula :

  C44H69NO12

• Molecular Weight :

  804.02

• Precautions :

  H301

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [129212-35-7]