Rofleponide

• UNSPSC Description:

  Rofleponide is a synthetic glucocorticoid that has a high affinity for rat thymic glucocorticoid receptors and has high anti-inflammatory efficacy in experimental animal models[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/rofleponide.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OCC([C@]12[C@@]3([C@@]([C@@]4([H])[C@]([C@H](C3)O)([C@@]5(C([C@H](C4)F)=CC(CC5)=O)C)F)([H])C[C@@]1([H])O[C@H](O2)CCC)C)=O

• Molecular Weight:

  468.53

• References & Citations:

  [1]Thalén A, et al. Synthesis and structure elucidation of potential 6-oxygenated metabolites of (22R)-6α, 9α-difluoro-11β, 21-dihydroxy-16α, 17α-propylmethylenedioxypregn-4-ene-3, 20-dione, and related glucocorticosteroids[J]. Steroids, 2000, 65(1): 16-23.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  Phase 2

• CAS Number:

  144459-70-1