4-Octyl itaconate
CAT:
804-HY-112675-03
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
4-Octyl itaconate
- CAS Number: 3133-16-2
- UNSPSC Description: 4-Octyl Itaconate is a cell-permeable Itaconate derivative. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1[1].
- Target Antigen: Keap1-Nrf2
- Type: Reference compound
- Related Pathways: NF-κB
- Applications: COVID-19-immunoregulation
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/4-octyl-itaconate.html
- Purity: 99.98
- Solubility: DMSO : 100 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 80°C)
- Smiles: O=C(OCCCCCCCC)CC(C(O)=O)=C
- Molecular Weight: 242.31
- References & Citations: [1]Mills EL, et al. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. Nature. 2018 Apr 5;556(7699):113-117.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: No Development Reported