4-Octyl itaconate-13C5-1

4-Octyl itaconate-13C5-1

• UNSPSC Description: 4-Octyl itaconate-13C5-1 is 13C-labeled 4-Octyl itaconate (HY-112675). Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
• Target Antigen: Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Others
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/4-octyl-itaconate-13c5-1.html
• Solubility: 10 mM in DMSO
• Smiles: CCCCCCCCO[13C]([13CH2][13C]([13C](O)=O)=[13CH2])=O
• Molecular Weight: 247.27
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Mills EL, et al. Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. Nature. 2018 Apr 5;556(7699):113-117.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported