LP-130

• Description :

  LP-130 is a statin-based inhibitor that is a universal inhibitor with nanomolar inhibitory activity against all tested retroviral proteases. Crystal structure studies of its binding to different retroviral proteases have shown that it can adapt to different active site regions to achieve inhibition.

• UNSPSC :

  12352209

• Target :

  Virus Protease

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/lp-130.html

• Smiles :

  NC([C@H](CC1=CC=CC2=C1C=CC=C2)NC([C@H](CC)NC(C[C@H](O)[C@H](CC(C)C)NC([C@H](C(C)C)NC([C@@H](NC(C)=O)CC3=CC=CC4=C3C=CC=C4)=O)=O)=O)=O)=O

• Molecular Formula :

  C45H58N6O7

• Molecular Weight :

  794.98

• References & Citations :

  [1]Toward a universal inhibitor of retroviral proteases: comparative analysis of the interactions of LP-130 complexed with proteases from HIV-1, FIV, and EIAV

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [153314-49-9]