CAL-130

• Description:

  CAL-130 is a PI3Kδ and PI3Kγ inhibitor with IC50s of 1.3 and 6.1 nM, respectively.

• UNSPSC:

  12352005

• Target:

  PI3K

• Type:

  Reference compound

• Related Pathways:

  PI3K/Akt/mTOR

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/cal-130.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1N(C2=CC=CC=C2C)C([C@H](C)NC3=C4N=CNC4=NC(N)=N3)=NC5=C1C(C)=CC=C5

• Molecular Formula:

  C23H22N8O

• Molecular Weight:

  426.47

• References & Citations:

  [1]Subramaniam Prem S, et al. Targeting nonclassical oncogenes for therapy in T-ALL. Cancer cell (2012), 21 (4), 459-72.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  PI3Kα; PI3Kβ; PI3Kγ; PI3Kδ

• CAS Number:

  [1431697-74-3]