EGFR-IN-130

CAT: 0804-HY-168173Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-168173Size:1 Each

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Description

EGFR-IN-130 (compound 14b) is an EGFR inhibitor and apoptosis inducer. EGFR-IN-130 triggers death of HeLa cancer cells via apoptosis induction.[1].

UNSPSC

12352005

Target

EGFR

Type

Reference compound

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Applications

COVID-19-immunoregulation

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/egfr-in-130.html

Smiles

OC1=C(CN(C2=CC(C(OC)=O)=C(O)C=C2)C3=NC(/C(S3)=C/C4=CC=C(N(C)C)C=C4)=O)C=C(O)C=C1

Molecular Formula

C27H25N3O6S

Molecular Weight

519.57

References & Citations

[1]Othman SA, et al. Combining lavendustin C and 5-arylidenethiazolin-4-one-based pharmacophores toward multitarget anticancer hybrids. Bioorg Chem. 2024 Dec;153:107884.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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HY-100028-01	AT-130
HY-103010-01	MSX-130
HY-101860-01	GIBH-130
HY-120757	LP-130
HY-121648	PK 130
HY-16122A	CAL-130
HY-114248	AGM-130
HY-100028R	AT-130 (Standard)
HY-173428	Antifungal agent 130
HY-16122	CAL-130 (Racemate)

Alternative Products

Catalog	Name
T201686-01	EGFR-IN-130
BA1833-5.1	AT-130
AR-B06300-01	AT 130
cyt-536-01	IL16, (130 a.a.)
EAA05159-01	MSX-130
T4450-01	GIBH-130
468336-01	TRV-130
255842-01	ML 130
B1192-5	HA 130
MBS5774169	LP 130

EGFR-IN-130

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