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NSC-70220

CAT: 0804-HY-101796-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-101796-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NSC-70220 is a selective and allosteric SOS1 inhibitor. NSC-70220 inhibits allosteric site activation, and partially inhibited catalytic site activation. NSC-70220 has an anticancer effect[1].
CAS Number
4551-00-2
UNSPSC
12352005
Target
Ras; SOS1
Type
Reference compound
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/SOS1-IN-1.html
Purity
99.42
Solubility
DMSO : 12.5 mg/mL (ultrasonic)
Smiles
O=[N+]([O-])C1=CC=CC=C1/C=C/C=C2C3=CC=CC=C3C4=CC=CC=C\24
Molecular Formula
C22H15NO2
Molecular Weight
325.36
References & Citations
[1]ARYL SULFONOHYDRAZIDES. WO 2016077793A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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Alternative Products

CatalogName
EAA55100-01NSC-70220
A13160-25NSC-70220 (SOS1-IN-1) 25mg
A13160-2NSC-70220 (SOS1-IN-1) 2mg
A13160-50NSC-70220 (SOS1-IN-1) 50mg
A13160-10NSC-70220 (SOS1-IN-1) 10mg
A13160-5NSC-70220 (SOS1-IN-1) 5mg
A13160-100NSC-70220 (SOS1-IN-1) 100mg
MBS8506140-01NSC 131463 (NSC 133723)
A4496-50NSC 3852
BA4984-25NSC-370284

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