Loperamide oxide (Standard)

• UNSPSC Description:

  Loperamide oxide (Standard) is the analytical standard of Loperamide oxide. This product is intended for research and analytical applications. Loperamide oxide (R-58425) is a orally active prodrug of the Loperamide (HY-156131). Loperamide oxide incubation with the contents of the intestinal lumen inhibits fluid secretion under aerobic conditions[1][2].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/loperamide-oxide-standard.html

• Smiles:

  O=C(C(C1=CC=CC=C1)(CC[N@+]2(CC[C@](C3=CC=C(C=C3)Cl)(CC2)O)[O-])C4=CC=CC=C4)N(C)C

• Molecular Weight:

  493.04

• References & Citations:

  [1]Hardcastle J, et al. The effect of loperamide oxide on prostaglandin-stimulated fluid transport in rat small intestine. J Pharm Pharmacol. 1990;42(5):364-366. |[2]Kamali F, Huang ML. Increased systemic availability of loperamide after oral administration of loperamide and loperamide oxide with cotrimoxazole. Br J Clin Pharmacol. 1996;41(2):125-128.

• Shipping Conditions:

  Room temperature

• CAS Number:

  106900-12-3