Loperamide oxide (Standard)

Loperamide oxide (Standard)

• CAS Number: 106900-12-3
• UNSPSC Description: Loperamide oxide (Standard) is the analytical standard of Loperamide oxide. This product is intended for research and analytical applications. Loperamide oxide (R-58425) is a orally active prodrug of the Loperamide (HY-156131). Loperamide oxide incubation with the contents of the intestinal lumen inhibits fluid secretion under aerobic conditions[1][2].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/loperamide-oxide-standard.html
• Smiles: O=C(C(C1=CC=CC=C1)(CC[N@+]2(CC[C@](C3=CC=C(C=C3)Cl)(CC2)O)[O-])C4=CC=CC=C4)N(C)C
• Molecular Weight: 493.04
• References & Citations: [1]Hardcastle J, et al. The effect of loperamide oxide on prostaglandin-stimulated fluid transport in rat small intestine. J Pharm Pharmacol. 1990;42(5):364-366. |[2]Kamali F, Huang ML. Increased systemic availability of loperamide after oral administration of loperamide and loperamide oxide with cotrimoxazole. Br J Clin Pharmacol. 1996;41(2):125-128.
• Shipping Conditions: Room temperature