KP 544

CAT: 0804-HY-11055Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-11055Size:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KP 544 is a potent neurotrophic protein enhancer that amplifies nerve growth factor (NGF) -induced neurite outgrowth of PC12 cells and SH-SY5Y neuroblastoma cells. KP544 also enhances choline acetyltransferase activity. KP 544 selectively interact in the differentiation pathway downstream of MAPK in a manner that amplifies nerve growth factor and cyclic AMP effects and is also neuroprotective[1].
CAS Number
[393856-87-6]
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/kp-544.html
Smiles
O[C@H]1CC[C@H](NC2=NC(N)=NC=C2C#CC3=CC=C(Cl)C=C3)CC1
Molecular Formula
C18H19ClN4O
Molecular Weight
342.82
References & Citations
[1]Fyfe J A, et al. KP544 amplifies the effects of nerve growth factor on cell differentiation and is neuroprotective[J]. Drug development research, 2004, 62 (1) : 49-59.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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