KP-6

• Description :

  KP-6, a polypeptide, is a Wnt/β-catenin signal inhibitor. KP-6 inhibits TGF-β and blocks rush fibrosis signal path crucial in vivo. KP-6 suppresses Renal tissues damage and renal fibrosis, and reverse the course of disease of chronic kidney disease (CKD) [1].

• UNSPSC :

  12352209

• Target :

  Wnt; β-catenin

• Type :

  Peptides

• Related Pathways :

  Stem Cell/Wnt

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/kp-6.html

• Smiles :

  OC(C=C1)=CC=C1C[C@H](NC([C@H](CC(C)C)NC([C@H]([C@H](O)C)NC([C@H](C(C)C)NC([C@H](C(C)C)NC([C@H]2N(CCC2)C([C@@H](N)CCC(N)=O)=O)=O)=O)=O)=O)=O)C(N[C@@H](CC3=CN=CN3)C(N[C@H](C(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(N4[C@@H](CCC4)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](C)C(N[C@H](C(NCC(NCC(N[C@H](C(N[C@@H](C)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CC(O)=O)C(N[C@H](C(O)=O)CC5=CN=CN5)=O)=O)=O)=O)=O)=O)=O)=O)CC6=CNC7=CC=CC=C67)=O)=O)=O)CC8=CC=C(C=C8)O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC9=CNC%10=CC=CC=C9%10)=O)=O

• Molecular Formula :

  C159H232N46O44

• Molecular Weight :

  3491.83

• References & Citations :

  [1]Youhua Liu, et al. Purposes of the micromolecule polypeptide KP 6 in the medicine for preparing treatment CKD. CN106822865A.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• CAS Number :

  [2102414-23-1]