KP-6

• Description:

  KP-6, a polypeptide, is a Wnt/β-catenin signal inhibitor. KP-6 inhibits TGF-β and blocks rush fibrosis signal path crucial in vivo. KP-6 suppresses Renal tissues damage and renal fibrosis, and reverse the course of disease of chronic kidney disease (CKD) [1].

• UNSPSC:

  12352209

• Target:

  Wnt; β-catenin

• Type:

  Peptides

• Related Pathways:

  Stem Cell/Wnt

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/kp-6.html

• Smiles:

  OC (C=C1) =CC=C1C[C@H] (NC ([C@H] (CC (C) C) NC ([C@H] ([C@H] (O) C) NC ([C@H] (C (C) C) NC ([C@H] (C (C) C) NC ([C@H]2N (CCC2) C ([C@@H] (N) CCC (N) =O) =O) =O) =O) =O) =O) =O) C (N[C@@H] (CC3=CN=CN3) C (N[C@H] (C (N[C@@H] (CC (O) =O) C (N[C@@H] (CC (C) C) C (N4[C@@H] (CCC4) C (N[C@@H] (CCC (N) =O) C (N[C@@H] (CCCNC (N) =N) C (N[C@@H] (CC (C) C) C (N[C@@H] (CCC (N) =O) C (N[C@@H] (CC (O) =O) C (N[C@@H] (C) C (N[C@H] (C (NCC (NCC (N[C@H] (C (N[C@@H] (C) C (N[C@@H] (CC (N) =O) C (N[C@@H] (CCCNC (N) =N) C (N[C@@H] (C) C (N[C@@H] (CC (C) C) C (N[C@@H] (C) C (N[C@@H] (CC (O) =O) C (N[C@H] (C (O) =O) CC5=CN=CN5) =O) =O) =O) =O) =O) =O) =O) =O) CC6=CNC7=CC=CC=C67) =O) =O) =O) CC8=CC=C (C=C8) O) =O) =O) =O) =O) =O) =O) =O) =O) =O) =O) CC9=CNC%10=CC=CC=C9%10) =O) =O

• Molecular Formula:

  C159H232N46O44

• Molecular Weight:

  3491.83

• References & Citations:

  [1]Youhua Liu, et al. Purposes of the micromolecule polypeptide KP 6 in the medicine for preparing treatment CKD. CN106822865A.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• CAS Number:

  2102414-23-1