PG-PS

• UNSPSC Description:

  PG-PS is a complex composed of streptococcal cell wall peptidoglycans and polysaccharides with pro-inflammatory and arthritis-inducing activity. PG-PS can be used to establish arthritis models. PG-PS can cause inflammation and joint damage, increase the expression of pro-inflammatory cytokines (TNF-α and IL-1β), and disrupt cellular redox balance[1][2].

• Target Antigen:

  Interleukin Related; TNF Receptor

• Type:

  Natural Products

• Related Pathways:

  Apoptosis;Immunology/Inflammation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/pg-ps.html

• Smiles:

  [PG-PS]

• References & Citations:

  [1]Vaillant, et al. "Ozone oxidative postconditioning ameliorates joint damage and decreases pro-inflammatory cytokine levels and oxidative stress in PG/PS-induced arthritis in rats." European journal of pharmacology 714.1-3 (2013): 318-324.|[2]Garcia, et al. "Prasugrel Aggravates the Inflammatory Response in a PG-PS-Induce Arthritis Model." (2011): 3268-3268.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported