PG 34

• Description:

  PG 34 is a weak O-GlcNAc transferase (OGT) inhibitor (IC50=68 μM), and a close structural analog of OSMI-1 (HY-119738) [1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  OGT

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/pg-34.html

• Purity:

  98.0

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(N1)C=CC2=C1C=CC(S(N[C@H](CC3=CC=CC=C3)C(N(CC4=CC=CO4)CC5=CC=CS5)=O)(=O)=O)=C2

• Molecular Formula:

  C28H25N3O5S2

• Molecular Weight:

  547.65

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Rodrigo F Ortiz-Meoz, et al. A small molecule that inhibits OGT activity in cells. ACS Chem Biol. 2015 Jun 19;10 (6) :1392-7.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture and light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1681056-62-1]