PDE1C1 (Human, Recombinant)

• Description:

  PDE1C1 (Human, Recombinant)_x000D_ Catalog number: B2017338_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 50 µg_x000D_ Molecular Weight or Concentration: 100 kDa_x000D_ Supplied as: Powder_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: −80°C_x000D_ Keywords: 3',5'-cyclic-AMP Phosphodiesterase 1C1, 3',5'-cyclic-GMP Phosphodiesterase 1C1, Calcium/Calmodulin-dependent 3',5'-cyclic Nucleotide Phosphodiesterase 1C1, Cam-PDE1C1, Phosphodiesterase 1C1, HCam3a_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Vandeput F, Wolda SL, Krall J, Hambleton R, Uher L, McCaw KN, Radwanski PB, Florio V, Movsesian MA. Cyclic nucleotide phosphodiesterase PDE1C1 in human cardiac myocytes J Biol Chem. 2007 Nov 9;282(45):32749-57._x000D_ 2: Shimizu K, Murata T, Watanabe Y, Sato C, Morita H, Tagawa T. Characterization of phosphodiesterase 1 in human malignant melanoma cell lines Anticancer Res. 2009 Apr;29(4):1119-22._x000D_ 3: Kelly MP, Adamowicz W, Bove S, Hartman AJ, Mariga A, Pathak G, Reinhart V, Romegialli A, Kleiman RJ. Select 3',5'-cyclic nucleotide phosphodiesterases exhibit altered expression in the aged rodent brain Cell Signal. 2014 Feb;26(2):383-97._x000D_ 4: Loughney K, Martins TJ, Harris EA, Sadhu K, Hicks JB, Sonnenburg WK, Beavo JA, Ferguson K. Isolation and characterization of cDNAs corresponding to two human calcium, calmodulin-regulated, 3',5'-cyclic nucleotide phosphodiesterases J Biol Chem. 1996 Jan 12;271(2):796-806._x000D_ 5: Yan C, Zhao AZ, Bentley JK, Beavo JA. The calmodulin-dependent phosphodiesterase gene PDE1C encodes several functionally different splice variants in a tissue-specific manner J Biol Chem. 1996 Oct 11;271(41):25699-706._x000D_ 6: Essayan DM. Cyclic nucleotide phosphodiesterase (PDE) inhibitors and immunomodulation Biochem Pharmacol. 1999 May 1;57(9):965-73._x000D_ 7: Brescia M, Zaccolo M. Modulation of Compartmentalised Cyclic Nucleotide Signalling via Local Inhibition of Phosphodiesterase Activity Int J Mol Sci. 2016 Oct 2;17(10):1672._x000D_ 8: Uckert S, Kuczyk MA. Cyclic nucleotide metabolism including nitric oxide and phosphodiesterase-related targets in the lower urinary tract Handb Exp Pharmacol. 2011;(202):527-42._x000D_ 9: Maurice DH. Cyclic nucleotide phosphodiesterase-mediated integration of cGMP and cAMP signaling in cells of the cardiovascular system Front Biosci. 2005 May 1;10:1221-8._x000D_ 10: Keravis T, Lugnier C. Cyclic nucleotide phosphodiesterase (PDE) isozymes as targets of the intracellular signalling network: benefits of PDE inhibitors in various diseases and perspectives for future therapeutic developments Br J Pharmacol. 2012 Mar;165(5):1288-305. _x000D_ _x000D_ Products Related to PDE1C1 (Human, Recombinant) can be found at Proteins

• Short Description:

  Catalog Number: B2017338 (50 µg)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3