PDE1B1 (Human, Recombinant)

• Description:

  PDE1B1 (Human, Recombinant)_x000D_ Catalog number: B2017269_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 50 µg_x000D_ Molecular Weight or Concentration: 89.2 kDa_x000D_ Supplied as: Powder_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: −80°C_x000D_ Keywords: Calcium/Calmodulin-dependent 3',5'-Cyclic Nucleotide Phosphodiesterase 1B, Cam-PDE 1B, Phosphodiesterase 1B1_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Yu J, Wolda SL, Frazier AL, Florio VA, Martins TJ, Snyder PB, Harris EA, McCaw KN, Farrell CA, Steiner B, Bentley JK, Beavo JA, Ferguson K, Gelinas R. Identification and characterisation of a human calmodulin-stimulated phosphodiesterase PDE1B1 Cell Signal. 1997 Nov;9(7):519-29._x000D_ 2: Polli JW, Kincaid RL. Expression of a calmodulin-dependent phosphodiesterase isoform (PDE1B1) correlates with brain regions having extensive dopaminergic innervation J Neurosci. 1994 Mar;14(3 Pt 1):1251-61._x000D_ 3: Bender AT, Ostenson CL, Wang EH, Beavo JA. Selective up-regulation of PDE1B2 upon monocyte-to-macrophage differentiation Proc Natl Acad Sci U S A. 2005 Jan 11;102(2):497-502._x000D_ 4: Jiang X, Li J, Paskind M, Epstein PM. Inhibition of calmodulin-dependent phosphodiesterase induces apoptosis in human leukemic cells Proc Natl Acad Sci U S A. 1996 Oct 1;93(20):11236-41._x000D_ 5: Polli JW, Kincaid RL. Molecular cloning of DNA encoding a calmodulin-dependent phosphodiesterase enriched in striatum Proc Natl Acad Sci U S A. 1992 Nov 15;89(22):11079-83._x000D_ 6: Subbotina A, Ravna AW, Lysaa RA, Abagyan R, Bugno R, Sager G. Inhibition of PDE5A1 guanosine cyclic monophosphate (cGMP) hydrolysing activity by sildenafil analogues that inhibit cellular cGMP efflux J Pharm Pharmacol. 2017 Jun;69(6):675-683._x000D_ 7: Fidock M, Miller M, Lanfear J. Isolation and differential tissue distribution of two human cDNAs encoding PDE1 splice variants Cell Signal. 2002 Jan;14(1):53-60._x000D_ 8: Das SB, Dinh C, Shah S, Olson D, Ross A, Selvakumar P, Sharma RK. Calmodulin-dependent cyclic nucleotide phosphodiesterase (PDE1) splice variants from bovine cardiac muscle Gene. 2007 Jul 15;396(2):283-92._x000D_ 9: Jiang X, Paskind M, Weltzien R, Epstein PM. Expression and regulation of mRNA for distinct isoforms of cAMP-specific PDE-4 in mitogen-stimulated and leukemic human lymphocytes Cell Biochem Biophys. 1998;28(2-3):135-60._x000D_ 10: Xue Q, Kang R, Klionsky DJ, Tang D, Liu J, Chen X. Copper metabolism in cell death and autophagy Autophagy. 2023 Aug;19(8):2175-2195. _x000D_ _x000D_ Products Related to PDE1B1 (Human, Recombinant) can be found at Proteins

• Short Description:

  Catalog Number: B2017269 (50 µg)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3