PSB-16131

• Description:

  PSB-16131 is a potent inhibitor of human NTPDase2, showing non-competitive inhibition with an IC50 of 539 nM. PSB-16131 can be used in the study of inflammation, neurodegenerative diseases and cancer[1].

• UNSPSC:

  12352005

• Target:

  NTPDase

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Inflammation/Immunology; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/psb-16131.html

• Purity:

  99.94

• Solubility:

  DMSO : 25 mg/mL (ultrasonic)

• Smiles:

  O=S(C1=CC(NC2=CC3=CC=CC=C3C4=CC=CC=C42)=C(C(C5=C6C=CC=C5)=O)C(C6=O)=C1N)(O[Na])=O

• Molecular Formula:

  C28H17N2NaO5S

• Molecular Weight:

  516.50

• References & Citations:

  [1]Development of Anthraquinone Derivatives as Ectonucleoside Triphosphate Diphosphohydrolase (NTPDase) Inhibitors With Selectivity for NTPDase2 and NTPDase3

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  NTPDase2

• CAS Number:

  [1213268-80-4]