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BMH-9

CAT: 0804-HY-118912Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-118912Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BMH-9 (Compound Z54) is a modulator for nuclear receptor subfamily 2, group F, member 6 (NR2F6) (also known as nuclear orphan receptor Ear2) [1]. BMH-9 is an activator for p53 signaling pathway through interaction with DNA. BMH-9 inhibits proliferation of human cancer cells, exhibits antitumor efficacy in NOD-SCID mouse models[1].
CAS Number
457937-39-2
UNSPSC
12352005
Target
MDM-2/p53; Orphan Nuclear Receptor; Orphan Receptor
Type
Reference compound
Related Pathways
Apoptosis; GPCR/G Protein; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/bmh-9.html
Smiles
O=C(OCC)C1=C(C2=CC(C)=CC(C)=C2N=C1)NCCCN(C)C
Molecular Formula
C19H27N3O2
Molecular Weight
329.44
References & Citations
[1]Lander HM, et al., Small Molecule Agonists and Antagonists of NR2F6 Activity in Humans. US20180214413.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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